Areas of work of the Institute of Nanotechnologies

1. Design and research of structural and phase characteristics of oxide heterostructures for photovoltaics and solar energy
2. Optimization of synthesis methods for nanostructured materials based on semiconductors of groups A3B5, A2B6, Si, SiC, etc.
3. Radiation defects in semiconductors and dielectrics
4. Research of ceramics synthesized under a powerful electron beam
5. Development and testing of photocatalytic materials for air and water purification in environmentally unfriendly regions
6. Energy efficiency and enhancement of materials for thermoelectric converters aimed at reducing the use of traditional energy resources
7. Study of ethical aspects of the application of nanotechnologies
8. Training of specialists in the field of nanotechnologies with a focus on interdisciplinary research and innovative teaching methodologies
9. Development of nanomaterials to improve energy-saving efficiency in industrial and residential buildings
10. Modeling and simulation of nanostructures for efficient interaction with renewable energy sources

Institute staff:

1. Yana Sychikova – director of the institute, Doctor of Technical Sciences, professor, vice-rector for scientific work of the BDPU https://www.scopus.com/authid/detail.uri?authorId=36523907500
2. Yaroslav Zhidachevsky – Doctor of Technical Sciences, senior research fellow, professor of the Department of Physics and Methods of Teaching Physics https://www.scopus.com/authid/detail.uri?authorId=6603506739
3. Sergiy Kovachov – research fellow https://www.scopus.com/authid/detail.uri?authorId=57208748653
4. Anastasiya Lysak – lead specialist https://www.scopus.com/authid/detail.uri?authorId=57221481509
5. Kateryna Tykhovod – lead specialist https://www.scopus.com/authid/detail.uri?authorId=57778310000&origin=recordpage

International cooperation:

The institute closely cooperates with the Institute of Physics of the University of Latvia (Latvia), Institute of Solid State Physics of the Polish Academy of Sciences (Poland), Eurasian National University (Kazakhstan)

Research is conducted at Synchrotron Radiation Centers:

• Max IV Beamline “FinEstBeAMS” Proposal ID 20220500,
• DESY Photon Science PETRA III beamline P66,
• League of European Accelerator-based Photon Sources – LEAPS – National Synchrotron Radiation Centre SOLARIS

State budget scientific projects:

• 0117U003860 “Development of technology for assessing the quality and safety indicators of nanotechnology products throughout the lifecycle”
• 0121U109426 “Theoretical and methodological principles of the systemic fundamentalization of the training of future specialists in the field of nanomaterials for productive professional activity”
• 0122U000129 “Searching for optimal conditions for the synthesis of nanostructures on the surface of A3B5, A2B6 semiconductors and silicon for photonics and solar energy” (2022 – 2025)
• 0116U006961 “Nanostructured semiconductors for energy-efficient environmentally safe technologies that increase the level of energy conservation and ecological safety of the urban system”
• 0123U100110 System of remote and blended specialized training of future nanoengineers for the development of new dual-use nanomaterials, 2023-2025

Competition “Cambridge – NFSU 2022. Individual grants for conducting research (developments) for Ukrainian scientists (supported by the University of Cambridge, United Kingdom)”:

“Design and research of oxide heterostructures for portable solar cells” (project leader – Yana Sychikova)

Membership in organizations and associations:

• COST CA20129 – Multiscale Irradiation and Chemistry Driven Processes and Related Technologies (MultIChem), Management Committee Member from Ukraine
• COST CA20129 – Multiscale Irradiation and Chemistry Driven Processes and Related Technologies (MultIChem) member of the working groups:

WG 1. Irradiation- and chemistry-driven multiscale phenomena

WG 2. Intersectoral cooperation on research and innovation

WG 3. Multiscale approach-based technological advances

WG 4. Training, dissemination, and outreach;

• COST Action CA20126 – Network for research, innovation and product development on porous semiconductors and oxides (NETPORE) member of the working groups:

WG 1. Advances in Porous Materials and Technologies

WG5. Management and Dissemination.

• Max IV Beamline «FinEstBeAMS» Proposal ID 20220500, member of the working group, Swedish government, 2022;
• DESY Photon Science PETRA III beamline P66, member of the working group, German government, 2023;
• League of European Accelerator Based-Photon Sources – LEAPS – SOLARIS National Synchrotron Radiation Centre
• Member of the Dissertation Committee on Doctoral and PhD these defenses D 18.092.01 in specialties 13.00.02 – theory and methods of teaching (Physics), 13.00.04 – theory and methods of professional education (Berdyansk State Pedagogical University);
• Member of the SCEINCE_AT_RISK_reload working group.

Contract research themes:

• Monitoring and development of recommendations regarding energy efficiency for small enterprises
• Manufacturing of material samples, namely plates of porous indium phosphide on a monocrystalline substrate
• Manufacturing of material samples, namely plates of porous gallium phosphide on a monocrystalline substrate

List of obtained protective documents for intellectual property objects:

• Patent for utility model No. u201810246 “Method for obtaining macroporous gallium arsenide with medium porosity level” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810247 “Method for obtaining macroporous gallium phosphide with low porosity level” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810253 “Method for obtaining mesoporous indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810291 “Method for obtaining low-porosity layers on the surface of indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No.u201810292 “Method for obtaining high-porosity gallium arsenide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6
• Patent for utility model No.u201810251 “Method for obtaining textured nanostructures on the surface of indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 10.05.2019, bulletin No. 9.
• Sychikova Y.O., Kovachov S.; Bogdanov I. Method for obtaining microporous gallium phosphide by electrochemical etching. Patent Pat. 150700, bulletin No. 11/2022
• Sychikova Y.O., Bogdanov I.; Kovachov S.; Lazarenko A.; Shyshkin G.; Bondarenko V.; Pimenov D.; Tykhovod K.; Medvedenko O. Method for obtaining high-porosity layers of zinc selenide. Patent 150697, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I. Method for obtaining track pores on the surface of n-type conductivity indium phosphide. Patent 150661, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G. Method of chemical polishing of indium phosphide surface. Patent 150660, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A. Method of obtaining periodic porous nanostructures on the surface of highly doped phosphide. Patent 150659, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A. Method of obtaining nanostructures on the surface of highly doped phosphide, packed in a “parquet” pattern. Patent 150658, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G. Method for obtaining mesoporous gallium phosphide. Patent 150657, 10/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G.; Bondarenko V.; Pimenov D.; Tykhovod K.; Medvedenko O.; Yefimenko Y. Method for obtaining a mesoporous layer on the surface of zinc selenide. Patent 150656, 10/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G.; Bondarenko V. Method for obtaining chain pores on the surface of indium phosphide by electrochemical etching. Patent 150655, 10/2022
• List of obtained protective documents for intellectual property objects:
• Patent for utility model No. u201810246 “Method for obtaining macroporous gallium arsenide with medium porosity level” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810247 “Method for obtaining macroporous gallium phosphide with low porosity level” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810253 “Method for obtaining mesoporous indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No. u201810291 “Method for obtaining low-porosity layers on the surface of indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6.
• Patent for utility model No.u201810292 “Method for obtaining high-porosity gallium arsenide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 25.03.2019, bulletin No. 6
• Patent for utility model No.u201810251 “Method for obtaining textured nanostructures on the surface of indium phosphide” / Y.O. Sychikova, I.T. Bogdanov. S.S. Kovachov. Owner: Berdyansk State Pedagogical University. Publ.: 10.05.2019, bulletin No. 9.
• Sychikova Y.O., Kovachov S.; Bogdanov I. Method for obtaining microporous gallium phosphide by electrochemical etching. Patent Pat. 150700, bulletin No. 11/2022
• Sychikova Y.O., Bogdanov I.; Kovachov S.; Lazarenko A.; Shyshkin G.; Bondarenko V.; Pimenov D.; Tykhovod K.; Medvedenko O. Method for obtaining high-porosity layers of zinc selenide. Patent 150697, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I. Method for obtaining track pores on the surface of n-type conductivity indium phosphide. Patent 150661, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G. Method of chemical polishing of indium phosphide surface. Patent 150660, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A. Method of obtaining periodic porous nanostructures on the surface of highly doped phosphide. Patent 150659, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A. Method of obtaining nanostructures on the surface of highly doped phosphide, packed in a “parquet” pattern. Patent 150658, 11/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G. Method for obtaining mesoporous gallium phosphide. Patent 150657, 10/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G.; Bondarenko V.; Pimenov D.; Tykhovod K.; Medvedenko O.; Yefimenko Y. Method for obtaining a mesoporous layer on the surface of zinc selenide. Patent 150656, 10/2022
• Sychikova Y.O., Kovachov S.; Bogdanov I.; Lazarenko A.; Shyshkin G.; Bondarenko V. Method for obtaining chain pores on the surface of indium phosphide by electrochemical etching. Patent 150655, 10/2022

List of important publications:

• Sergii Kovachov, Ihor Bohdanov, Yana Suchikova (2023). “Nano or Na-No? Ukraine’s Crisis of Opportunity in Nanotechnology Education”. Industry and Higher Education (in press) https://journals.sagepub.com/toc/IHE/0/0
• Yana Suchikova, Gennady Shishkin, Iryna Bardus, Ihor Bohdanov, Mariia Skurska, Kateryna Starostenko. Training Prospective Nanotechnologists to Select Optimum Solutions for the Nanostructures Synthesis Using the Analytic Hierarchy Process. TEM Journal, 2021, 10(4), P. 1796–1802. https://www.temjournal.com/content/104/TEMJournalNovember2021_1796_1802.html
• Suchikova, Y., Kovachov, S., Bohdanov, I., Pankratov, V., & Popov, A. I. (2023). Study of the structural and morphological characteristics of the CdxTeyOz nanocomposite obtained on the surface of the CdS/ZnO heterostructure by the SILAR method. Applied Physics A: Materials Science and Processing, 129(7), 499.  https://link.springer.com/article/10.1007/s00339-023-06776-x
• Suchikova, Y., Kovachov, S., Bohdanov, I., Moskina, A., & Popov, A. (2023). Characterization of CdxTeyOz/CdS/ZnO heterostructures synthesized by the SILAR method. Coatings, 13(3), 639. https://www.mdpi.com/2079-6412/13/3/639
• Suchikova, Y., Kovachov, S., Lazarenko, A., Нurenko, O., & Bohdanov, I. (2023). Surface modification of gallium arsenide by electrochemical methods in different electrolyte compositions. Chemistry and Chemical Technology, 17(2), 262-271.
• Kovachov, S., Bohdanov, I., Bardus, I., Kosogov, I., & Suchikova, Y. (2023). About synthesis mechanism of periodic oxide nanocrystallites on surface of single-crystal. Physics and Chemistry of Solid State, 24(1), 159-165. https://journals.pnu.edu.ua/index.php/pcss/article/view/6317
• Suchikova, Y., Kovachov, S., Bohdanov, I., Abdikadirova, A. A., Kenzhina, I., & Popov, A. I. (2023). Electrochemical Growth and Structural Study of the AlxGa1− xAs Nanowhisker Layer on the GaAs Surface. Journal of Manufacturing and Materials Processing, 7(5), 153. https://www.mdpi.com/2504-4494/7/5/153
• Suchikova, Y., Kovachov, S., Lazarenko, A., Bohdanov, I. Research of synthesis conditions and structural features of heterostructure AlXGa1-XAs/GaAs of the “desert rose” type. Applied Surface Science Advances.2022, 12, 100327 https://www.sciencedirect.com/science/article/pii/S2666523922001179
• Suchikova, Y., Kovachov, S., Bohdanov, I. Formation of oxide crystallites on the porous GaAs surface by electrochemical deposition. Nanomaterials and Nanotechnology. 2022, 12 https://journals.sagepub.com/doi/full/10.1177/18479804221127307
• Lazarenko, A.S., Tikhovod, K.M., Kovachov, S.S., Bohdanov, I.T., Sychikova, Y.O. Calculation of the Energy Spectrum of Quantum Particle in Double Potential Pit. Metallofizika i Noveishie Tekhnologii. 2022, 44(8), pp. 963–974 https://mfint.imp.kiev.ua/article/v44/i08/MFiNT.44.0963.pdf
• Suchikova, Y.O., Kovachov, S.S., Lazarenko, A.S., …Hurenko, O.I., Bohdanov, I.T. Oxidation of the n-GaAs Surface: Morphological and Kinetic Analysis. Journal of Nano- and Electronic Physics. 2022, 14(3), 03033 https://essuir.sumdu.edu.ua/handle/123456789/88480
• O. Suchikova, S.S. Kovachov, I.O. Bardus, I.T. Bohdanov. Formation of β-SiC on por-Si/mono-Si surface according to Stranski – Krastanow mechanism. Chemistry, Physics and Technology of Surface. 2022. V. 13. N 4. P. 447-454 https://www.researchgate.net/profile/Yana-Suchikova/publication/366698515_Formation_of_b-SiC_on_por-Simono-Si_surface_according_to_stranski_-_krastanow_mechanism/links/63ba6122097c7832ca9ceb0b/Formation-of-b-SiC-on-por-Si-mono-Si-surface-according-to-stranski-krastanow-mechanism.pdf
• Suchikova, Y., Bohdanov, I., Kovachov, S., …Kenzhina, I., Popov, A.I. Synthesis of porous indium phosphide with nickel oxide crystallites on the surface. Journal of Electrochemical Science and Engineering, 2022, 12(4), P. 593–601. https://pub.iapchem.org/ojs/index.php/JESE/article/view/1301
• Suchikova, Ya., Lazarenko, A., Kovachov, S., Bohdanov, I. Nanostructures on the ZnSe Surface: Synthesis, Morphological and Photoluminescent Properties. Physics and Chemistry of Solid State, 2021, 22(4), P. 614–620. https://journals.pnu.edu.ua/index.php/pcss/article/view/5157
• Vambol, S.O., Bogdanov, I.T., Vambol, V.V., Suchikova, Ya.O., Kovachov, S.S. Correlation between technological factors of synthesis of por-gap and its acquired properties. Nanosistemi, Nanomateriali, Nanotehnologii. 2018, 16, № 4, Р. 657–670. https://www.researchgate.net/publication/332780381_Correlation_between_Technological_Factors_of_Synthesis_of_por-GaP_and_Its_Acquired_Properties
• Suchikova, Ya.O., Bogdanov, I.T., Kovachov, S.S. Oxide crystals on the surface of porous indium phosphide. Archives of Materials Science and Engineering, 2019, 98/2, P. 49–56. https://dspace.bdpu.org/bitstream/123456789/776/1/Suchikova%20Y.%20O.%20Oxide%20crystals%20on%20the%20 surface%20of%20porous%20indium%20phosphide%20.pdf
• Suchikova, Y.O., Bogdanov, I.T., Kovachov, S.S., Myroshnychenko, V.O., Panova, N.Y. Optimal ranges determination of morphological parameters of nanopatterned semiconductors quality for solar cells. Archives of Materials Science and Engineering, 2020, 101(1), P.15–24. http://31.186.81.235:8080/api/files/view/1156834.pdf
• Sychikova, Y.O., Bogdanov, I.T., Kovachov, S.S Influence of current density of anodizing on the geometric characteristics of nanostructures synthesized on the surface of semiconductors of A3B5 group and silicon. Functional Materials, 2019, 27(1), P.29–34. http://functmaterials.org.ua/contents/27-1/29
• Suchikova Y., Bogdanov I., Kovachov S., Lopatina H., Tsybuliak N., Panova N. Research of the Structure of Nanomaterials by Analysis of Micromorphology Images. Nanosistemi, Nanomateriali, Nanotehnologii. 2020, V. 18, № 4, Р. 875–888. https://www.researchgate.net/publication/350040620_Research_of_the_Structure_of_Nanomaterials_by_Analysis _of_Micromorphology_Images
• Suchikova, Y.O., Kovachov, S.S., Shishkin, G.O., …Bondarenko, V.V., Bogdanov, I.T. Functional model for the synthesis of nanostructures of the given quality level. Archives of Materials Science and Engineering, 2021, 107(2), P. 72–84. https://archivesmse.org/resources/html/article/details?id=217751
• S. Kovachov, I.T. Bogdanov, D.O. Pimenov, V.V. Bondarenko, A.A. Konovalenko, M.M. Skurska, I.S. Konovalenko, Y.O. Suchikova. Chemical evaluation of the quality of nanostructures synthesized on the surface of indium phosphide. Archives of Materials Science and Engineering, 2021, 110 (1), Р. 18–26. https://doi.org/10.5604/01.3001.0015.3592
• Suchikova, Ya., Lazarenko, A., Kovachov, S., Bohdanov, I. Nanostructures on the ZnSe Surface: Synthesis, Morphological and Photoluminescent Properties. Physics and Chemistry of Solid State, 2021, 22(4), P. 614–620. https://journals.pnu.edu.ua/index.php/pcss/article/view/5157
• Kryvylova O., Oleksenko K., Kotelianets N., Kotelianets Y., Kindei L., Kushnirova T. Influence of the state reform of primary education on the professional training of future teachers. Cuestiones políticas. Vol. 40 Nº75 (2022): 134-144 https://produccioncientificaluz.org/index.php/cuestiones/article/view/39264
• Kushlyk, M., Tsiumra, V., Zhydachevskyy, Y., Aleszkiewicz, M., Suchocki, A. (2022). Preparation and properties of Ag plasmonic structures on garnet substrates. Applied Nanoscience (Switzerland), 12(3), 317-334. https://link.springer.com/article/10.1007/s13204-020-01624-3
• Przybylińska, H., Zhydachevskyy, Y., Grochot, A., Berkowski, M., Suchocki, A. (2022). Electron Paramagnetic Resonance and Optical Studies of Thermoluminescence Processes in Mn-Doped YAlO3 Single Crystals. Journal of Physical Chemistry C, 126(1), 743-753. https://pubs.acs.org/doi/10.1021/acs.jpcc.1c08997
• Baran, M., Belikov, K.N., Kissabekova, A., Zazubovich, S., Zhydachevskyy, Y. (2022). Luminescence and energy transfer processes in LuNbO4:Bi, Eu. Optical Materials, 123, 111948. https://www.sciencedirect.com/science/article/abs/pii/S0925346721011484?via%3Dihub
• Altunal, V., Guckan, V., Ozdemir, A., Yu, Y., Zhydachevskyy, Y.. (2022). Three newly developed BeO-based OSL dosimeters. Journal of Luminescence, 241, 118528. https://www.sciencedirect.com/science/article/abs/pii/S002223132100644X?via%3Dihub
• Zhydachevskyy, Y., Hizhnyi, Y., Nedilko, S.G., Suchocki, A., Klyui, N. (2021). Band Gap Engineering and Trap Depths of Intrinsic Point Defects in RAlO3(R = Y, La, Gd, Yb, Lu) Perovskites. Journal of Physical Chemistry C, 125(48), 26698-26710. https://pubs.acs.org/doi/10.1021/acs.jpcc.1c06573
• Stadnik, V., Hreb, V., Luchechko, A., Suchocki, A., Zhydachevskyy, Y., Vasylechko, L. (2021). Sol-gel combustion synthesis, crystal structure and luminescence of Cr3+ and Mn4+ ions in nanocrystalline SrAl4O7. Inorganics, 9(12), 89. https://www.mdpi.com/2304-6740/9/12/89
• Mykhaylyk, V.B., Kraus, H., Bulyk, L.-I., Wagner, A., Zhydachevskyy, Y., Suchocki, A. (2021). Al2O3 co-doped with Cr3+ and Mn4+, a dual-emitter probe for multimodal non-contact luminescence thermometry. Dalton Transactions, 50(41), 14820-14831. https://pubs.rsc.org/en/content/articlelanding/2021/DT/D1DT02836G
• Krasnikov, A., Tsiumra, V., Vasylechko, L., Zazubovich, S., Zhydachevskyy, Y. (2021). Photostimulated Defect Creation Processes in the Undoped and Bi3+-Doped Ca3Ga2Ge3O12 Garnets. Physica Status Solidi (B) Basic Research, 258(10), 2100080. https://onlinelibrary.wiley.com/doi/10.1002/pssb.202100080
• Altunal, V., Guckan, V., Ozdemir, A., Zydhachevskyy, Y., Yegingil, Z. (2021). A systematic study on luminescence characterization of lanthanide-doped BeO ceramic dosimeters. Journal of Alloys and Compounds, 876, 160105. https://www.sciencedirect.com/science/article/abs/pii/S0925838821015140?via%3Dihub
• Kozanecki, A., Sajkowski, J.M., Mathew, J.A., Zhydachevskyy, Y., Alves, E., Stachowicz, M. (2021). Enhanced red emission from Eu-implanted ZnMgO layers and ZnO/ZnMgO quantum structures. Applied Physics Letters, 119(11), 112101. https://pubs.aip.org/aip/apl/article-abstract/119/11/112101/39929/Enhanced-red-emission-from-Eu-implanted-ZnMgO?redirectedFrom=fulltext
• Mosafer, H.S.R., Paszkowicz, W., Minikayev, R., Zhydachevskyy, Y., Nedilko, S. (2023). Crystal Structure, Thermal Expansion and Luminescence of Ca10.5−xNix(VO4)7. Crystals, 13(5), 853. https://www.mdpi.com/2073-4352/13/5/853
• Hreb, V., Lutsyuk, I., Stadnik, V., Wojciechowski, T., Zhydachevskyy, Y., Vasylechko, L. (2023). Sol–gel derived ZnAl2O4 nanopowders co-doped with Cr3+, Er3+ and Yb3+ ions. Applied Nanoscience (Switzerland). https://link.springer.com/article/10.1007/s13204-023-02899-y